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Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
Published on: August 16, 2020
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Microscopic brain tumor detection and classification using 3D CNN and feature selection architecture.
Amjad Rehman1, Muhammad Attique Khan2, Tanzila Saba1
1Artificial Intelligence & Data Analytics Lab CCIS, Prince Sultan University, Riyadh, Saudi Arabia.
Microscopy Research and Technique
|September 22, 2020
Summary
This study introduces a deep learning method for precise brain tumor detection and classification from MRI scans. The novel approach achieves high accuracy, aiding in faster and more reliable diagnoses.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Oncology
Background:
- Brain tumors represent a significant global health challenge, causing numerous deaths annually.
- Accurate and timely diagnosis is crucial for effective treatment and improved patient survival rates.
- Current diagnostic methods require improvement, highlighting the need for automated techniques in brain tumor grading.
Purpose of the Study:
- To develop and validate a deep learning-based method for microscopic brain tumor detection and classification.
- To enhance the precision of brain tumor grading using advanced computational techniques.
- To address the limitations of existing methods by proposing a novel automated approach.
Main Methods:
- A 3D convolutional neural network (CNN) was designed for initial brain tumor extraction.
- Pre-trained CNN models were employed for feature extraction from the segmented tumors.
- Correlation-based feature selection and a feed-forward neural network were utilized for final classification.
Main Results:
- The proposed deep learning method achieved high accuracy rates on multiple BraTS datasets (2015, 2017, 2018): 98.32%, 96.97%, and 92.67%, respectively.
- Feature selection using the correlation-based method effectively identified the most relevant features for classification.
- The overall performance demonstrated the efficacy of the proposed automated technique in brain tumor analysis.
Conclusions:
- The developed deep learning model offers a precise and automated solution for brain tumor detection and classification.
- The method shows comparable accuracy to existing techniques, suggesting its potential for clinical application.
- This approach can aid radiologists and oncologists in making faster and more accurate diagnoses, potentially improving patient outcomes.

