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Morbidity and Mortality Patterns in Children Admitted to Hospital in Thai Binh, Vietnam: A Five-year Descriptive
Thi Dung Pham1, Van Thuan Hoang1,2,3, Thi Loi Dao1,2,3
1Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.
Insights
Infectious diseases are the leading cause of illness and death in children at Thai Binh Paediatric Hospital. Improved diagnostic tools are needed for better treatment and antibiotic use.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Children in Vietnam face significant morbidity and mortality.
- Infectious diseases are a major contributor to pediatric health issues.
Purpose of the Study:
- To describe pediatric morbidity and mortality patterns at Thai Binh Paediatric Hospital.
- To identify the prevalence of infectious diseases in hospitalized children.
- To inform the need for improved diagnostic tools and antibiotic stewardship.
Main Methods:
- Retrospective review of 113,999 hospitalization records from January 2015 to December 2019.
- Analysis of patient demographics, diagnoses, treatment, and outcomes.
- Focus on infectious disease patterns and their contribution to mortality.
Main Results:
- Infectious diseases comprised 61.0% of cases, with lower respiratory tract infections being most common.
- Antibiotics were administered to 81.4% of patients, often without microbiological documentation.
- Infectious diseases accounted for 40.4% of deaths, highlighting a critical need for better diagnostics.
Conclusions:
- Pediatric infectious diseases pose a substantial burden in Vietnam.
- There is a clear need for enhanced diagnostic capabilities, such as point-of-care tests.
- Improved diagnostics can lead to more accurate diagnoses and appropriate antibiotic use, reducing mortality.
Abstract:
The objective of this study was to describe the overall pattern of morbidity and mortality of children seen at the Thai Binh Paediatric Hospital in Vietnam, with a focus on infectious diseases. A retrospective review of hospitalisation records was conducted from 1 January 2015 to 31 December 2019. Data were obtained from a total of 113,999 records. The median age of patients was 18 months, with 84.0% of patients aged <5 years. Infectious diseases accounted for 61.0% of all cases. The most prevalent diseases were lower respiratory tract infections (32.8%), followed by gastrointestinal infections (13.3%) and confirmed influenza (5.4%). Most infections were not microbiologically documented. A total of 81.4% patients received at least one antibiotic. Most patients (97.0%) were hospitalised for less than 15 days. Regarding outcomes, 87.8% patients were discharged home with a favourable outcome. Twelve percent were transferred to the Vietnam National Children's Hospital because their condition had worsened and 0.1% died. In total, infectious diseases accounted for 40.4% of deaths, followed by neonatal disorders (34.6%). Our data serves a basis for the identification of needs for diagnostic tools and for future evaluation of the effect of the targeted implementation of such facilities. Point-of-care tests, including real-time polymerase chain reaction assays to identify common pathogens should be implemented for more accurate diagnosis and more appropriate antibiotic use.
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