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Updated: Dec 8, 2025

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
Published on: February 22, 2015
Gliomas, germ cell tumors, and craniopharyngioma
Paul Aridgides1, Geert O Janssens2, Steve Braunstein3
1Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, NY, 13210.
Abstract:
This report summarizes the current multimodality treatment approaches for children with low- and high-grade gliomas, germinoma, and nongerminomatous germ cell tumors, and craniopharyngiomas used in the Children's Oncology Group (COG) and the International Society of Pediatric Oncology (SIOP). Treatment recommendations are provided in the context of historical approaches regarding the roles of surgery, radiation, and chemotherapy. Future research strategies for these tumors in both COG and SIOP are also discussed.
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