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Related Concept Videos

Positive and Negative Feedback Loops01:18

Positive and Negative Feedback Loops

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Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires  maintaining an internal dynamic equilibrium:
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What is Homeostasis?01:16

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Maintaining homeostasis requires that the body continuously maintain its internal conditions. Each physiological condition has a particular set point, from body temperature to blood pressure to levels of certain nutrients. A set point is the physiological value around which the normal range fluctuates. A normal range is a restricted set of values that is optimally healthful and stable. For example, the set point for normal human body temperature is approximately 37°C (98.6°F).
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pH Homeostasis01:31

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Acid-base homeostasis is essential for maintaining normal physiological activities in humans. The pH of various body fluids is strictly regulated because it is critical for the optimal activity of enzymes involved in metabolic reactions. Enzymes are basically proteins, so, any significant change in pH can affect their structure and activity. In humans, pH is regulated using three primary mechanisms— chemical buffer systems, respiratory regulation, and renal regulation.
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Non-equilibrium in the Cell01:16

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An important concept in studying metabolism and energy is that of chemical equilibrium. Most chemical reactions are reversible. They can proceed in both directions, releasing energy into their environment in one direction, and absorbing it from the environment in the other direction. The same is true for the chemical reactions involved in cell metabolism, such as the breaking down and building up of proteins into and from individual amino acids, respectively. Reactants within a closed system...
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Tissue Renewal without Stem Cells01:23

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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Homeostatic Imbalance01:10

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Homeostasis is the maintenance of a stable internal environment within the body, which is crucial for the proper functioning of cells, tissues, organs, and organ systems. The body has various control mechanisms that work together to regulate various physiological parameters such as temperature, blood pressure, pH balance, and fluid balance, to name a few. These control mechanisms are based on feedback loops that can be either positive or negative.
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Related Experiment Video

Updated: Dec 8, 2025

Measurement of Smooth Muscle Function in the Isolated Tissue Bath-applications to Pharmacology Research
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Homeostasis Tissue-Like P Systems.

Yueguo Luo, Yuzhen Zhao, Changchuan Chen

    IEEE Transactions on Nanobioscience
    |September 22, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Homeostasis tissue-like P systems were developed, removing environmental energy dependence. These systems demonstrate Turing universality and can solve NP-complete problems, reflecting biological homeostasis.

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    Area of Science:

    • Theoretical Computer Science
    • Computational Biology
    • Formal Systems

    Background:

    • Tissue P systems are distributed parallel computing models inspired by biological cells and their environment.
    • Existing models rely on environmental energy, creating a dependency that limits their autonomy.
    • Biological homeostasis describes an organism's ability to maintain internal stability despite external changes.

    Purpose of the Study:

    • To introduce a novel computational model, homeostasis tissue-like P systems, by incorporating multiset rewriting rules and removing environmental energy dependency.
    • To demonstrate the computational power and problem-solving capabilities of this new model.
    • To establish a connection between computational systems and biological homeostasis.

    Main Methods:

    • Introduction of multiset rewriting rules into tissue P systems.
    • Development of a computational model named homeostasis tissue-like P systems.
    • Construction of uniform solutions for the 3-coloring problem and the SAT problem.

    Main Results:

    • Two uniform solutions were constructed in feasible time: one for 3-coloring in linear time and another for SAT in time-free mode.
    • The constructed system can generate any Turing computable set of numbers.
    • The system operates independently of the environment, mirroring biological homeostasis.

    Conclusions:

    • Homeostasis tissue-like P systems are a novel computational model that does not rely on environmental energy.
    • These systems exhibit Turing universality and can effectively solve NP-complete problems, even in a time-free mode.
    • The model successfully reflects the biological phenomenon of homeostasis in a computational context.