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Updated: Dec 8, 2025

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
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Alcohol intake reduction for controlling hypertension.

Maria Teresa Acin1, José-Ramón Rueda2, Luis Carlos Saiz3

  • 1Drug Prescribing Service, Navarre Health Service, Pamplona, Spain.

The Cochrane Database of Systematic Reviews
|September 22, 2020
PubMed
Summary
This summary is machine-generated.

Reducing alcohol intake did not significantly lower blood pressure in hypertensive individuals. While alcohol consumption decreased, there were no observed changes in mortality or cardiovascular events in this study.

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Area of Science:

  • Cardiovascular Medicine
  • Public Health
  • Addiction Medicine

Background:

  • High blood pressure (hypertension) is a major global health concern.
  • Heavy alcohol consumption is a known risk factor for cardiovascular diseases, including hypertension.
  • The impact of interventions aimed at reducing alcohol intake on blood pressure is not well understood.

Purpose of the Study:

  • To evaluate the effect of interventions reducing alcohol intake on blood pressure in hypertensive individuals.
  • To assess secondary outcomes such as mortality, major cardiovascular events, serious adverse events, and quality of life.

Main Methods:

  • Searched multiple databases for randomized controlled trials (RCTs) up to June 2020.
  • Included RCTs with a minimum 12-week duration, ≥50 participants/group, and quantitative alcohol measurement.
  • Included adults with hypertension (systolic blood pressure >140 mmHg or diastolic blood pressure >90 mmHg).

Main Results:

  • One RCT with 269 participants and a two-year follow-up was included.
  • No significant differences in systolic or diastolic blood pressure reduction between intervention and control groups.
  • Alcohol intake was significantly reduced in the intervention group, but no differences in mortality or cardiovascular events were found.

Conclusions:

  • Interventions to decrease alcohol intake did not lead to significant blood pressure changes in hypertensive individuals.
  • A significant reduction in alcohol consumption was observed in the intervention group.
  • Further high-quality RCTs are needed to confirm these findings and assess other outcomes.