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Contemplating HPV vaccination in Japan during the time of COVID-19
Ai Miyoshi1, Yutaka Ueda1, Tadashi Kimura1
1Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Insights
Human papillomavirus (HPV) vaccination is crucial for preventing cervical cancer in Japan, with a fatality rate comparable to COVID-19. Increased HPV vaccination uptake is recommended for public health.
Area of Science:
- Oncology
- Public Health
- Vaccinology
Background:
- The Coronavirus Disease 2019 (COVID-19) pandemic is a growing global health concern.
- Human papillomavirus (HPV) infection is prevalent in Japan, leading to significant cancer risks.
- Japan has a notably low cervical cancer screening rate among developed nations.
Purpose of the Study:
- To highlight the comparable fatality rates of HPV-associated cancers and COVID-19.
- To address the low HPV vaccination rates in Japan following MHLW's recommendation suspension.
- To advocate for increased HPV vaccination acceptance among women.
Main Methods:
- Comparative analysis of fatality rates for COVID-19 and HPV-associated cancers.
- Review of HPV vaccination trends in Japan post-2013.
- Examination of public health messaging regarding vaccination.
Main Results:
- The fatality rate for HPV-associated cancers in Japan is comparable to that of COVID-19.
- HPV vaccination rates in Japan have drastically declined from 70% to below 1% since 2013.
- Media reports on alleged adverse events influenced public perception and policy.
Conclusions:
- HPV vaccination is essential for preventing cervical cancer, a serious health threat in Japan.
- Public health initiatives should encourage HPV vaccination with the same urgency as COVID-19 testing.
- Addressing concerns and restoring confidence in HPV vaccination is critical for improving women's health outcomes.
Abstract:
The Coronavirus Disease 2019 (COVID-19) pandemic has been growing, including in Japan where it has been estimated that as many as 3.1% of patients positive for new CoV strain SARS-CoV-2 might die of COVID-19-related respiratory failure. Meanwhile, human papillomavirus (HPV) is spreading in Japan. The fatality rate for HPV-associated cancers after infection with HPV is as much as that for COVID-19 in Japan, although the time to disease is much longer for HPV. Among advanced countries, the cervical cancer screening rate in Japanese females is very low. The Japanese Ministry of Health, Labor and Welfare (MHLW) suspended its official recommendation for HPV vaccination in June 2013 due to alleged adverse post-vaccination events in several young girls, such as chronic pain and motor impairment, which were repeatedly reported in the media. Subsequently, the rate for vaccinating girls plummeted from approximately 70% to the current rate of 1% or less. Women should accept HPV vaccination for the eventual prevention of cervical cancer with the same passion they are for COVID-19 testing.
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