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Updated: Dec 8, 2025

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Published on: December 8, 2023
Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system
Nina Marí G P de Queiroz1, Fabio V Marinho1, Marcelo A Chagas1
1Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Abstract:
This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.
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