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Study Profile of the Japan Multi-institutional Collaborative Cohort (J-MICC) Study
Kenji Takeuchi1, Mariko Naito1,2, Sayo Kawai1,3
1Department of Preventive Medicine, Nagoya University Graduate School of Medicine.
Journal of Epidemiology
|September 23, 2020
Summary
The Japan Multi-institutional Collaborative Cohort (J-MICC) study enrolled over 90,000 participants to investigate gene-environment interactions in lifestyle diseases. This valuable cohort provides data for research on longer, healthier lives.
Area of Science:
- Epidemiology
- Genetics
- Public Health
Background:
- The Japan Multi-institutional Collaborative Cohort (J-MICC) study initiated in 2005.
- Focuses on gene-environment interactions in lifestyle-related diseases, including cancers, within the Japanese population.
Purpose of the Study:
- To describe the study design and baseline characteristics of J-MICC participants.
- To establish a comprehensive cohort for investigating factors influencing lifestyle-related diseases.
Main Methods:
- Recruited 92,610 adults aged 35-69 from diverse regions in Japan.
- Collected detailed data on demographics, lifestyle factors, medical history, and biospecimens (blood samples).
- Data collection occurred between 2005 and 2014.
Main Results:
- The baseline cohort comprised 92,610 participants (44.1% male, mean age 55.2 years).
- Participation rates varied by region (19.7% to 69.8%).
- Observed differences in BMI, education, alcohol, smoking, and sleep between genders.
Conclusions:
- The J-MICC Study successfully established a large cohort with extensive lifestyle and clinical data.
- This cohort serves as a significant resource for national and international research.
- Aims to contribute evidence supporting increased healthy lifespans.
