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[Pulmonary blastomycosis]
Fatma Chermiti Ben Abdallah1, Imène Bachouch1, Nidhal Belloumi1
1Service de Pneumologie IV, Faculté de Médecine de Tunis, Hôpital Abderrahmen Mami Ariana, Tunis, Tunisie.
The Pan African Medical Journal
|September 23, 2020
Summary
This case study details a rare Blastomycosis infection in Tunisia, mimicking tuberculosis. Early diagnosis and antifungal treatment with itraconazole led to patient recovery, highlighting diagnostic challenges.
Area of Science:
- Mycology
- Infectious Diseases
- Pulmonology
Background:
- Blastomycosis is a rare fungal infection caused by *Blastomyces dermatitidis*, primarily affecting the lungs.
- Pulmonary blastomycosis presents with diverse clinical symptoms, from asymptomatic cases to life-threatening conditions.
Observation:
- A 35-year-old Tunisian patient presented with chronic cough, chest pain, fever, and weight loss.
- Physical examination revealed fever and a subcutaneous swelling near the T10 vertebra.
- Chest imaging showed bilateral opacities with excavations; sputum tests for tuberculosis were negative.
Findings:
- Anatomopathological examination of a dorsal mass biopsy confirmed Blastomycosis.
- Fungal cultures from the biopsy specimens validated the diagnosis.
- Treatment with itraconazole resulted in significant clinical and radiological improvement.
Implications:
- This case underscores the diagnostic difficulties of Blastomycosis in regions where it is uncommon, especially when symptoms overlap with tuberculosis.
- Timely diagnosis and appropriate antifungal therapy are crucial for favorable outcomes in Blastomycosis patients.
- Raising awareness among clinicians about rare fungal infections like Blastomycosis is essential for prompt management.
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