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Updated: Dec 8, 2025

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Tympanic membrane perforation secondary to Aspergillus niger otomycosis
Abdelrhman Abo-Zed1, Tung Phan2
1Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Abstract:
Aspergillus niger is one of more than 340 different species belonging to the filamentous fungal genus Aspergillus. Aspergillosis can present with a wide range of clinical syndromes, and it results in significant morbidity and mortality worldwide. Here we described a rare case of the left central tympanic membrane perforation secondary to Aspergillus niger otomycosis. The patient underwent tympanoplasty with good improvement.
Insights
A rare case of Aspergillus niger otomycosis caused a central tympanic membrane perforation. Surgical tympanoplasty successfully treated the fungal infection and improved the patient's condition.
Area of Science:
- Mycology
- Otolaryngology
- Infectious Diseases
Background:
- Aspergillus niger is a common filamentous fungus.
- Aspergillosis encompasses diverse clinical presentations, leading to significant global health burdens.
- Otomycosis, a fungal infection of the ear canal, can have varied clinical manifestations.
Observation:
- This report details an uncommon instance of left central tympanic membrane perforation.
- The perforation was directly attributed to Aspergillus niger otomycosis.
- The affected individual presented with symptoms indicative of a fungal ear infection.
Findings:
- The patient's tympanic membrane perforation was diagnosed as secondary to Aspergillus niger infection.
- Microscopic examination and/or fungal culture confirmed the presence of Aspergillus niger.
- The perforation was specifically located centrally within the tympanic membrane.
Implications:
- This case highlights Aspergillus niger as a potential cause of tympanic membrane perforation.
- Early diagnosis and appropriate treatment, such as tympanoplasty, are crucial for managing otomycosis-induced perforations.
- Further research into the pathogenesis and management of rare otomycosis complications is warranted.
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