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Relationship between Depression and Cognitive Impairment among Elderly: A Cross-sectional Study
Zahra Aajami1, Leila Kazazi2, Mahdi Toroski1
1Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Depression and cognitive impairment frequently affect older adults. This study found a significant link between these conditions, highlighting the need for integrated geriatric assessments.
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Depression and cognitive impairment are prevalent issues in the elderly population.
- Limited research exists on the co-occurrence of these conditions in aging individuals.
Purpose of the Study:
- To investigate the relationship between depression and cognitive impairment in older adults.
- To identify risk and protective factors associated with cognitive dysfunction in this demographic.
Main Methods:
- A cross-sectional, population-based study involving 506 older adults in Tehran, Iran.
- Data collected via sociodemographic questionnaire, Mini-Mental State Examination (MMSE), and Geriatric Depression Scale (GDS).
- Statistical analysis included correlation and logistic regression using SPSS-17.
Main Results:
- Older adults over 75 years showed a twofold increased risk of cognitive dysfunction.
- Significant correlation found between MMSE and GDS scores.
- Higher education and employment were associated with a reduced risk of cognitive dysfunction (85% and 56% lower, respectively).
- Severe depression was linked to a twofold increased risk of cognitive dysfunction.
Conclusions:
- A significant relationship exists between depression and cognitive impairment in the elderly.
- Integrated assessment of both cognitive function and depression is crucial in geriatric care.
- Findings underscore the importance of addressing mental health in aging populations to prevent cognitive decline.
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