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Michaela Plath1, Matthias Sand2, Philippe A Federspil1

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This study established normative values for the Tonsillectomy Outcome Inventory 14 (TOI-14) in healthy individuals. These values help assess the disease burden for tonsillectomy decisions.

Keywords:
EFAGuidelinesMiddle-european cohortPCAQuality of lifeRecurrent tonsillitisTOI-14

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Area of Science:

  • Otolaryngology
  • Health Outcomes Research
  • Quality of Life Measurement

Background:

  • The Tonsillectomy Outcome Inventory 14 (TOI-14) is used to assess outcomes after tonsillectomy.
  • Normative data is crucial for interpreting patient scores and understanding disease burden.
  • Previous studies have not established comprehensive normative values for a healthy population.

Purpose of the Study:

  • To determine normative values for the TOI-14 in a healthy middle-European cohort.
  • To compare TOI-14 scores between healthy individuals and patients with recurrent tonsillitis (RT).
  • To explore the factorial structure of the TOI-14.

Main Methods:

  • A reference cohort of 1000 healthy individuals was recruited via a market research panel, matched to German Microcensus data.
  • A clinical cohort of patients with RT was assessed pre- and post-tonsillectomy (6 and 12 months).
  • Principal component and exploratory factor analyses were used to analyze TOI-14 responses.

Main Results:

  • Principal component analysis identified three TOI-14 domains: physiological, psychological, and socio-economic, explaining 73% of variance.
  • Healthy individuals reported good quality of life with a mean TOI-14 total score of 11.8.
  • Patient cohort scores were higher than the reference cohort, confirming TOI-14's discriminative ability for RT. Age and gender influenced scores, particularly in psychological and socio-economic domains.

Conclusions:

  • Normative values for the TOI-14 have been established for a healthy population.
  • The TOI-14 effectively discriminates between patients with recurrent tonsillitis and healthy individuals.
  • These normative values aid in determining disease burden and guiding tonsillectomy decisions.