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Published on: May 19, 2011
A Thiourea-Containing Fluorescent Chemosensor for Detecting Ga3
Soyoung Park1, Hangyul Lee1, Ju Byeong Chae1
1Department of Fine Chem, Seoul National Univ. of Sci. and Tech. (SNUT), Seoul, 01811, South Korea.
Abstract:
A thiourea-based fluorescent chemosensor NADA, (E)-2-(4-(diethylamino)-2-hydroxybenzylidene)-N-(naphthalen-1-yl)hydrazine-1-carbothioamide, has been designed and synthesized. NADA could detect Ga3+ through a fluorescent turn-on with a low detection limit (0.29 μM). Importantly, NADA could effectively discriminate Ga3+ from Al3+ and In3+. The binding mechanism of NADA with Ga3+ was identified by ESI-mass, NMR titration, and DFT calculations.
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