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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

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Related Experiment Video

Updated: May 23, 2026

Quantitative Visualization of Leukocyte Infiltrate in a Murine Model of Fulminant Myocarditis by Light Sheet Microscopy
06:49

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Mike Wakelam: an appreciation.

Bob Michell1

  • 1School of Biosciences, University of Birmingham, Birmingham, U.K.

Essays in Biochemistry
|September 23, 2020
PubMed
Summary

This issue explores lipid mediators, which are biologically active molecules derived from fatty acids. These molecules play crucial roles in physiological processes but can become dysregulated in aging and diseases like diabetes and cancer.

Area of Science:

  • Biochemistry
  • Cell Biology
  • Molecular Medicine

Background:

  • Lipid mediators are biologically active metabolites from polyunsaturated fatty acid oxidation.
  • They function in cell signaling via autocrine and paracrine mechanisms.
  • Their dysregulation is implicated in aging and various diseases.

Discussion:

  • This issue is dedicated to Professor Mike Wakelam, a key figure in lipid signaling research.
  • It examines the multifaceted roles of lipid mediators in health and disease.
  • The importance of understanding lipid mediator pathways is highlighted.

Key Insights:

  • Lipid mediators are crucial signaling molecules with diverse physiological roles.
  • Dysregulation of lipid mediators is linked to aging and complex diseases.
Keywords:
autocrine pathwayslipid mediatorsmetabolismparacrine pathways

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Last Updated: May 23, 2026

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  • Further research into lipid mediators is essential for therapeutic advancements.

    • Outlook:

    • Future research will focus on the therapeutic potential of targeting lipid mediator pathways.
    • Understanding lipid mediator roles may lead to novel treatments for metabolic and inflammatory diseases.
    • Continued exploration of lipid signaling will advance our knowledge of cellular communication.