[Genomic studies to better understand the biological behavior of lung cancer]

Over the past 15 years, it has become evident that molecular genetic testing has a place in the management of lung cancer patients in routine clinical practice. Initial monogenic examinations are increasingly being replaced by genomic investigations that analyze multiple genes, or even hundreds of genes. In the present paper, the author briefly summarizes the main therapeutic targets for genomic study of non-small cell and small cell lung cancers. In addition, two exciting areas of genomic research through the results of international research with domestic participation are also presented: gene expression pattern analysis predicting lung cancer prognosis, and study on tumor evolution and genetic effect of oncotherapies.