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Safety, Efficacy, and Effectiveness of Delabeling in Patients with Multiple Drug Allergy Labels

Chandra Vethody1, Roger Yu1, Jacob M Keck2

  • 1Division of Allergy and Immunology, Department of Medicine, Vanderbilt Asthma Sinus and Allergy Program, Vanderbilt University Medical Center, Nashville, Tenn.

The Journal of Allergy and Clinical Immunology. in Practice
|September 23, 2020
PubMed
Abstract

Insights

Multiple drug allergy labels (MDALs) can be safely removed in a single visit, improving patient care. However, ensuring consistent label removal across healthcare providers requires further attention.

Area of Science:

  • Clinical Medicine
  • Allergy and Immunology
  • Pharmacology

Background:

  • Multiple drug allergy labels (MDALs) pose significant challenges in patient care.
  • Accurate allergy labeling is crucial for safe and effective medication management.

Purpose of the Study:

  • To evaluate the efficacy and safety of removing MDALs during a single clinical visit.
  • To assess the effectiveness of drug allergy label removal in improving patient care.

Main Methods:

  • Retrospective chart review of patients with MDALs from October 2014 to October 2018.
  • Analysis of allergy label testing, removal, and patient outcomes.
  • Post-visit surveys administered to patients, pharmacies, and primary care physicians.

Main Results:

  • Over 97% of tested allergy labels were successfully removed from electronic health records (EHRs).
  • Most patients (86%) were delabeled in a single visit, though 25% retained labels at one year.
  • Physician and pharmacy confirmation of label removal varied, highlighting communication gaps.

Conclusions:

  • Drug allergy label removal is safe and feasible in a single visit.
  • Barriers to the effectiveness of MDAL removal persist, particularly in information dissemination.
  • Improved communication strategies are needed to reinforce label removal with patients and providers.
Keywords:
AllergyDrugIntoleranceMultiple

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