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The Tubular Striatum.

Daniel W Wesson1

  • 1Department of Pharmacology & Therapeutics, University of Florida, College of Medicine, Gainesville, Florida 32610 danielwesson@ufl.edu.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|September 24, 2020
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Summary
This summary is machine-generated.

The olfactory tubercle (OT), long thought to be solely for smell, plays a broader role. New models suggest it integrates sensory and motivational information to guide behavior and emotional responses.

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Area of Science:

  • Neuroscience
  • Behavioral Neuroscience

Background:

  • The olfactory tubercle (OT) was historically named and classified as an olfactory cortex.
  • This classification is based on a mid-19th century misconception by Albert von Kölliker.

Purpose of the Study:

  • To challenge the purely olfactory role of the OT.
  • To propose a new model for the function of the OT, potentially renaming it the "tubular striatum" (TuS).

Main Methods:

  • Review and synthesis of existing research on OT functions.
  • Development of a theoretical model integrating sensory and motivational information processing.

Main Results:

  • Evidence suggests the OT is involved in functions beyond olfaction, including learning and motivated behaviors.
  • Research indicates the OT's role in seeking psychoactive drugs.

Conclusions:

  • The OT's function extends beyond olfaction.
  • A proposed model suggests the OT integrates sensory experiences with motivational states to guide affective and behavioral responses.
  • The term "tubular striatum" (TuS) may be a more accurate descriptor for the OT.