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[Non-ischemic ventricular dysfunction in COVID-19 patients: characteristics and implications for cardiac imaging on
Donato Mele1, Antonello D'Andrea2, Marco Campana3
1U.O.C. Cardiologia, Azienda Ospedaliero-Universitaria, Ferrara.
Insights
Coronavirus 2019 disease (COVID-19) can cause non-ischemic ventricular dysfunction, impacting heart function. This review explores its diagnostic challenges and implications using cardiac imaging during the pandemic.
Area of Science:
- Cardiology
- Infectious Diseases
- Oncology
Background:
- COVID-19, caused by SARS-CoV-2, presents with diverse cardiac manifestations, including heart failure and cardiogenic shock.
- Non-ischemic ventricular dysfunction is a recognized cardiac complication of COVID-19, potentially linked to myocarditis or stress/cytokine-related conditions.
- The diagnostic clarity, prevalence, and prognostic impact of these dysfunctions during COVID-19 remain incompletely understood.
Purpose of the Study:
- To review the multifaceted aspects of non-ischemic ventricular dysfunction in COVID-19 patients.
- To evaluate the diagnostic implications of cardiac imaging techniques for these conditions.
- To provide a comprehensive overview of current knowledge and identify research gaps.
Main Methods:
- Literature review focusing on non-ischemic ventricular dysfunction in the context of COVID-19.
- Analysis of diagnostic strategies, particularly cardiac imaging modalities.
- Synthesis of findings regarding prevalence, clinical presentation, and prognostic significance.
Main Results:
- COVID-19 is associated with various forms of non-ischemic ventricular dysfunction.
- Cardiac imaging plays a crucial role in diagnosing and characterizing these dysfunctions.
- Challenges in diagnosis and limited data on prevalence and prognosis persist.
Conclusions:
- Non-ischemic ventricular dysfunction is a significant cardiac complication of COVID-19 requiring careful evaluation.
- Cardiac imaging techniques are essential for timely diagnosis and management.
- Further research is needed to elucidate the full prevalence and prognostic implications.
Abstract:
Coronavirus 2019 disease (COVID-19), caused by SARS-CoV-2, can lead to cardiac impairment with various types of clinical manifestations, including heart failure and cardiogenic shock. A possible expression of cardiac impairment is non-ischemic ventricular dysfunction, which can be related to different pathological conditions, such as myocarditis, stress and cytokine-related ventricular dysfunction. The diagnosis of these pathological conditions can be challenging during COVID-19; furthermore, their prevalence and prognostic significance have not been elucidated yet. The purpose of this review is to take stock of the various aspects of non-ischemic ventricular dysfunction that may occur during COVID-19 and of the diagnostic implications related to the use of cardiac imaging techniques.
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