[Non-ischemic ventricular dysfunction in COVID-19 patients: characteristics and implications for cardiac imaging on

Donato Mele1, Antonello D'Andrea2, Marco Campana3

  • 1U.O.C. Cardiologia, Azienda Ospedaliero-Universitaria, Ferrara.

Giornale Italiano Di Cardiologia (2006)
|September 24, 2020
PubMed

Insights

Coronavirus 2019 disease (COVID-19) can cause non-ischemic ventricular dysfunction, impacting heart function. This review explores its diagnostic challenges and implications using cardiac imaging during the pandemic.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Oncology

Background:

  • COVID-19, caused by SARS-CoV-2, presents with diverse cardiac manifestations, including heart failure and cardiogenic shock.
  • Non-ischemic ventricular dysfunction is a recognized cardiac complication of COVID-19, potentially linked to myocarditis or stress/cytokine-related conditions.
  • The diagnostic clarity, prevalence, and prognostic impact of these dysfunctions during COVID-19 remain incompletely understood.

Purpose of the Study:

  • To review the multifaceted aspects of non-ischemic ventricular dysfunction in COVID-19 patients.
  • To evaluate the diagnostic implications of cardiac imaging techniques for these conditions.
  • To provide a comprehensive overview of current knowledge and identify research gaps.

Main Methods:

  • Literature review focusing on non-ischemic ventricular dysfunction in the context of COVID-19.
  • Analysis of diagnostic strategies, particularly cardiac imaging modalities.
  • Synthesis of findings regarding prevalence, clinical presentation, and prognostic significance.

Main Results:

  • COVID-19 is associated with various forms of non-ischemic ventricular dysfunction.
  • Cardiac imaging plays a crucial role in diagnosing and characterizing these dysfunctions.
  • Challenges in diagnosis and limited data on prevalence and prognosis persist.

Conclusions:

  • Non-ischemic ventricular dysfunction is a significant cardiac complication of COVID-19 requiring careful evaluation.
  • Cardiac imaging techniques are essential for timely diagnosis and management.
  • Further research is needed to elucidate the full prevalence and prognostic implications.

Related Concept Videos

Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
389
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
272
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
347
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
166
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
241
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
144