Multivisceral Resection of Advanced Pelvic Tumors: From Planning to Implementation

Area of Science:

• Oncology
• Surgical Oncology
• Gastroenterology

Background:

• Pelvic exenteration is a complex surgical procedure for advanced or recurrent pelvic malignancies.
• Historically associated with high morbidity, its application has been limited.
• Recent advancements have improved patient selection and perioperative care.

Purpose of the Study:

• To provide a contemporary overview of pelvic exenteration surgery.
• To summarize the current state of the art in managing pelvic tumors requiring this radical approach.
• To highlight improvements in patient outcomes and quality of life.

Main Methods:

• Review of current literature and clinical practices in pelvic exenteration.
• Analysis of advancements in tumor staging and oncological therapies.
• Evaluation of preoperative optimization, surgical techniques, and critical care.

Main Results:

• Pelvic exenteration can be safely performed in specialized centers.
• Carefully selected patients demonstrate a 5-year survival rate exceeding 60%.
• Low mortality and optimal post-operative quality of life are achievable.

Conclusions:

• Pelvic exenteration is a viable and effective treatment option for select patients with advanced pelvic tumors.
• Multidisciplinary care and optimized patient selection are crucial for successful outcomes.
• Continued advancements enhance the safety and efficacy of this radical surgery.