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Updated: Dec 8, 2025

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Dual-energy CT and coronary imaging
1Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Dual-energy computed tomography shows promise for evaluating coronary artery disease (CAD). This review examines the supporting evidence, practical uses, and challenges hindering its widespread clinical adoption for CAD.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Technology
Background:
- Dual-energy computed tomography (DECT) offers advanced capabilities for coronary artery disease (CAD) assessment.
- Despite its potential, the clinical integration of DECT for CAD evaluation has been gradual.
Purpose of the Study:
- To review the evidence base for DECT in evaluating coronary artery disease (CAD).
- To illustrate practical applications of DECT in CAD.
- To identify challenges and knowledge gaps impeding DECT's clinical translation for CAD.
Main Methods:
- Literature review of studies on DECT for coronary artery disease.
- Analysis of clinical evidence and practical case examples.
- Identification of barriers to clinical adoption.
Main Results:
- DECT provides valuable insights into coronary artery plaque characterization and stenosis assessment.
- Illustrative cases demonstrate DECT's utility in complex CAD scenarios.
- Key challenges include standardization, radiation dose, and cost-effectiveness.
Conclusions:
- DECT holds significant potential for improving coronary artery disease evaluation.
- Addressing current challenges is crucial for broader clinical implementation.
- Further research is needed to optimize DECT protocols and validate its long-term clinical impact in CAD.
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