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Strongyloides-specific IgA, IgG and IgG immune complex profile in patients with pulmonary tuberculosis
Larissa Rodrigues Bosqui1, Gabriela Borges da Silva2, Henrique Tomaz Gonzaga2
1Universidade Estadual de Londrina, UEL, Rodovia Celso Garcia Cid Campus Universitário, Londrina, Brazil.
Aims:
To describe an anti-Strongyloides IgA, IgG and IgG immune complex antibody response profile in patients with pulmonary tuberculosis.
Methods And Results:
Saliva and serum samples were collected from 100 individuals: group I, 50 apparently healthy individuals; and group II, 50 pulmonary tuberculosis patients. The IgA, IgG and IgG immune complex detection were carried out via an ELISA immunoenzymatic test. Optical density medians in saliva samples of IgA antibody (median of 7.21) and IgG-IC (median of 4.95) were significantly higher in tuberculosis group compared to control individuals (median IgA of 3.93 and IgG-IC of 2.38).
Conclusion:
This study presents antibody data to the field of pulmonary tuberculosis and strongyloidiasis coinfection, including saliva samples, and especially IgG immune complex detection.
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