Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

461
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
461
Dark Triad and Person Perception01:29

Dark Triad and Person Perception

151
Person perception is influenced by both external behaviors and the observer’s internal characteristics, including personality traits. Individuals with dark personality traits, comprising psychopathy, Machiavellianism, and narcissism — collectively known as the dark triad – exhibit manipulative and exploitative tendencies in social contexts. These traits affect how they perceive others and how they are perceived.The Role of Dark Personality Traits in Person PerceptionBlack et...
151
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.3K
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

459
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
459
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

395
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
395
Borderline Personality Disorder01:25

Borderline Personality Disorder

353
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
353

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Antidepressant discontinuation syndrome : recognition and management].

Revue medicale suisse·2026
Same author

Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.

Molecular psychiatry·2026
Same author

Managing metabolic syndrome in bipolar disorder: multidisciplinary monitoring and treatment strategies.

Frontiers in psychiatry·2026
Same author

Severe Lithium Toxicity due to the Use of Unauthorized Weight Loss Medication.

Bipolar disorders·2026
Same author

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder.

medRxiv : the preprint server for health sciences·2026
Same author

The Experience of Women With Breast or Gynecological Cancer After Participation in an Online Mindfulness-Based Cancer Recovery (e-MBCR) Program: Secondary Outcomes Analysis of a Pilot Mixed Methods Randomized Controlled Trial.

Psycho-oncology·2025

Related Experiment Video

Updated: Dec 8, 2025

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.0K

[Light - darkness and bipolar disorder].

Françoise Jermann1, Hélène Richard-Lepouriel1, Jean-Michel Aubry1

  • 1Service des spécialités psychiatriques, Département de psychiatrie, HUG, 1211 Genève 14.

Revue Medicale Suisse
|September 24, 2020
PubMed
Summary

Disruptions in the daily biological clock rhythm are linked to bipolar disorders. Modulating this clock with light or dark therapy shows potential for treatment, though more research is needed, especially for dark therapy.

Area of Science:

  • Chronobiology
  • Neuroscience
  • Psychiatry

Background:

  • Human functioning is regulated by a near-24-hour biological clock, synchronized by environmental cues like light.
  • Bipolar disorders exhibit disturbances suggestive of circadian rhythm disruption.
  • Treatments targeting the biological clock are being developed for bipolar disorder.

Purpose of the Study:

  • To review the role of circadian rhythm disruptions in bipolar disorder.
  • To evaluate current therapeutic interventions, including light and dark therapy.
  • To highlight the potential of dark therapy as a future research avenue.

Main Methods:

  • Literature review of studies on circadian rhythms and bipolar disorder.
  • Analysis of existing research on light therapy efficacy and limitations.

More Related Videos

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.2K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.1K

Related Experiment Videos

Last Updated: Dec 8, 2025

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.0K
Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.2K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.1K
  • Exploration of preliminary data and theoretical underpinnings of dark therapy.

    • Main Results:

    • Light therapy results for bipolar disorder are inconsistent, necessitating refined treatment protocols.
    • Circadian rhythm disturbances are a significant feature of bipolar disorder.
    • Dark therapy presents a novel, understudied intervention with promising therapeutic potential.

    Conclusions:

    • Modulating the biological clock is a viable strategy for bipolar disorder treatment.
    • Further research is crucial to optimize light therapy and fully investigate dark therapy's effectiveness.
    • Dark therapy offers a promising frontier for future research in managing bipolar disorder.