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Updated: Dec 8, 2025

Prostaglandin Extraction and Analysis in Caenorhabditis elegans
Published on: June 25, 2013
A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action
1College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, 5000 Lakewood Ranch Blvd, Bradenton, FL, 34211, USA. rbiringer@lecom.edu.
Abstract:
Prostaglandin signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain to cell survival. Disruption of normal prostanoid signaling is implicated in numerous disease states. Prostaglandin signaling is facilitated by G-protein-coupled, prostanoid-specific receptors and the array of associated G-proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of prostanoid receptors with particular emphasis on human isoforms.
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