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Updated: Dec 7, 2025

Super-Resolution Imaging of Bacterial Secreted Proteins Using Genetic Code Expansion
Published on: February 10, 2023
Super-resolution imaging of bacterial pathogens and visualization of their secreted effectors
Moirangthem Kiran Singh1, Linda J Kenney1
1Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Abstract:
Recent advances in super-resolution imaging techniques, together with new fluorescent probes have enhanced our understanding of bacterial pathogenesis and their interplay within the host. In this review, we provide an overview of what these techniques have taught us about the bacterial lifestyle, the nucleoid organization, its complex protein secretion systems, as well as the secreted virulence factors.
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