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Updated: Dec 7, 2025

A Molecular Readout of Long-term Olfactory Adaptation in C. elegans
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A Molecular Readout of Long-term Olfactory Adaptation in C. elegans

Published on: December 22, 2012

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Sensory Glia Detect Repulsive Odorants and Drive Olfactory Adaptation

Duo Duan1, Hu Zhang2, Xiaomin Yue2

  • 1Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China; Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.

Neuron
|September 24, 2020
PubMed
Summary

Glial cells actively participate in sensing smells. In C. elegans, AMsh glia use distinct receptors to suppress avoidance responses and promote olfactory adaptation by inhibiting ASH neurons.

Keywords:
C. elegansGABAergic inhibitiongliaolfactory adaptationolfactory transduction

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