Related Experiment Video
Updated: Dec 7, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Global Longitudinal Strain Predicts Survival and Left Ventricular Function After Mitral Valve Surgery: A
Martin Canessa1, Ritu Thamman2, Carlos Americo1
1National Institute of Cardiac Surgery, Montevideo, Uruguay.
Global longitudinal strain (GLS) predicts survival and left ventricular ejection fraction (LVEF) after mitral valve surgery for severe mitral regurgitation. Preoperative GLS is a valuable tool for guiding surgical timing in these patients.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Surgery
Background:
- Timing of surgical intervention for severe mitral regurgitation with preserved LVEF is challenging.
- LV end-systolic dimension and LVEF are late indicators of LV dysfunction.
- Echocardiography is crucial for diagnosing mitral regurgitation severity and consequences.
Purpose of the Study:
- To evaluate the role of global longitudinal strain (GLS) in predicting postoperative outcomes in patients with severe mitral regurgitation and preserved LVEF undergoing surgery.
- To determine if preoperative GLS can predict long-term survival and LV function post-mitral valve surgery.
Main Methods:
- A meta-analysis was conducted on 8 studies, including 2358 patients.
- Studies compared outcomes based on preoperative GLS in patients undergoing mitral valve surgery.
- Outcomes assessed included survival and postoperative LV function.
Main Results:
- Reduced preoperative GLS was associated with worse long-term survival after mitral valve surgery (HR = 1.13).
- Patients with reduced GLS showed lower LVEF post-surgery (MD = -5.06%).
- Postoperative LVEF dysfunction correlated with worse preoperative GLS (MD = 4.33).
Conclusions:
- Preoperative GLS is a significant predictor of long-term survival and postoperative LVEF in patients with primary mitral regurgitation.
- GLS is a valuable parameter for considering early surgical intervention in severe mitral regurgitation with normal LVEF.
More Related Videos
04:48Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
11:50High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
Published on: July 9, 2010
Related Concept Videos
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management
Mitral Regurgitation I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management