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Related Experiment Video

Updated: Dec 7, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Multicentric recurrent uveal melanoma.

Vikas Menon¹, Mithun Thulasidas¹, Ritesh Narula²

¹Ophthalmic Plastic Surgery and Ocular Oncology Services, Centre for Sight, New Delhi, India.

Indian Journal of Ophthalmology

|September 25, 2020

Summary

Multifocal uveal melanoma, rare in one eye, requires vigilant monitoring. This case report details three distinct uveal melanoma lesions in a single eye, emphasizing the need for close patient follow-up.

Keywords:

Brachytherapy choroidal melanoma ciliarybody melanoma enucleation

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Area of Science:

Ophthalmology
Oncology

Background:

Uveal melanoma is a rare eye cancer originating from melanocytes.
True multifocal uveal melanomas, defined as more than two lesions in one eye, are exceptionally uncommon.

Observation:

A patient presented with three distinct uveal melanoma lesions within the same eye over a 2.5-year period.
The patient's condition ultimately necessitated enucleation of the affected eye.

Findings:

Histological examination confirmed the diagnosis of multiple uveal melanomas in the enucleated eye.
The case documents a rare instance of aggressive, multifocal disease progression.

Implications:

This case underscores the critical importance of rigorous follow-up protocols for uveal melanoma patients, even after initial treatment.
Close monitoring may be necessary to detect and manage potential recurrence or new lesion development in the same eye.