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Heart failure as a manifestation of acromegaly

Ivana Ságová, Milan Dragula, Daniela Kantárová

    Vnitrni Lekarstvi
    |September 25, 2020
    PubMed

    Insights

    Acromegaly, a rare pituitary tumor disorder, causes serious heart issues. Early diagnosis of acromegaly is crucial for managing cardiovascular complications and improving patient outcomes.

    Area of Science:

    • Endocrinology
    • Cardiology
    • Rare Diseases

    Background:

    • Acromegaly results from excess growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often due to pituitary tumors.
    • Chronic GH/IGF-1 excess leads to significant cardiovascular, rheumatologic, and metabolic complications.
    • Cardiovascular diseases are the primary cause of mortality in acromegaly patients.

    Keywords:
    acromegalycardiomyopathyheart failurev growth hormone

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