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Gut Microbial Regulation of Autism Spectrum Disorder Symptoms
Ariane R Panzer1, Susan V Lynch1
1Division of Gastroenterology, University of California San Francisco, San Francisco, CA, USA; UCSF Benioff Center for Microbiome Medicine, University of California San Francisco, San Francisco, CA, USA.
Abstract:
Relationships between gut microbiome perturbation and autism spectrum disorder (ASD) have been observed in several human studies, but the functional implications and molecular mechanisms by which microbes may influence disease symptomology remain enigmatic. A recently published study by Sharon et al. offers evidence that the gut microbiome has a causative role in ASD and highlights the importance of early-life gut microbial metabolites in shaping mammalian behavior.
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