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Complete Coding Sequence of a Pasivirus Found in Swedish Pigs.

Giorgi Metreveli¹, Mikael Berg¹, Anne-Lie Blomström²

¹Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.

Microbiology Resource Announcements

|September 25, 2020

Summary

Researchers identified a novel pasivirus in Swedish pigs with respiratory illness. This virus shares significant genetic similarity with other global pasivirus strains.

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Area of Science:

Veterinary Virology
Molecular Biology
Animal Health

Background:

Pasiviruses are emerging RNA viruses that can affect livestock.
Respiratory diseases in pigs pose a significant threat to animal agriculture.
Surveillance of novel pathogens is crucial for disease control.

Purpose of the Study:

To characterize a newly identified pasivirus from a Swedish pig herd.
To determine the genetic relatedness of this virus to known pasiviruses.
To contribute to the understanding of pasivirus diversity and evolution.

Main Methods:

Viral RNA extraction and sequencing from pig tonsil samples.
Bioinformatic analysis of the complete coding sequence.
Comparative sequence analysis with reference pasivirus genomes.

Main Results:

The complete coding sequence of a novel pasivirus was successfully obtained.
The identified pasivirus genome showed 75-87% nucleotide and 81-94% amino acid identity to other pasiviruses.
The virus was detected in a pig from a herd experiencing respiratory disease.

Conclusions:

This finding expands the known genetic diversity of pasiviruses.
The characterized Swedish pasivirus is closely related to other global strains.
Further research is needed to assess the pathogenicity and epidemiological impact of this virus in swine populations.