The 2020 Pandemic: Current SARS-CoV-2 Vaccine Development

Area of Science:

• Virology
• Immunology
• Public Health

Background:

• Coronaviruses, including SARS-CoV and MERS-CoV, have caused severe human diseases.
• A novel coronavirus, SARS-CoV-2, emerged in late 2019, leading to the global Covid-19 pandemic.
• The pandemic has resulted in millions of cases and hundreds of thousands of deaths worldwide.

Purpose of the Study:

• To review the current landscape of vaccine development for SARS-CoV-2.
• To identify and summarize the most advanced vaccine candidates in clinical trials.
• To address the urgent need for effective vaccines to combat the Covid-19 pandemic.

Main Methods:

• Literature review of scientific publications and clinical trial databases.
• Analysis of vaccine candidates progressing through different phases of clinical development.
• Summary of the furthest vaccines in the clinical pipeline.

Main Results:

• Several vaccine candidates targeting SARS-CoV-2 are in various stages of clinical development.
• The review provides an overview of the leading vaccine candidates and their progress.
• No effective vaccines or therapies have been approved to date.

Conclusions:

• There is an urgent need for the development and approval of safe and effective SARS-CoV-2 vaccines.
• The ongoing research and clinical trials represent critical steps towards controlling the Covid-19 pandemic.
• Continued monitoring and summarization of vaccine development are essential.