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Selective N-Terminal BET Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water

Huarui Cui1, Anand Divakaran2, Anil K Pandey1

  • 1Department of Chemistry, University of Minnesota-Twin Cities, 207 Pleasant St. SE, Minneapolis, MN, 55455, USA.

Angewandte Chemie (International Ed. in English)
|September 25, 2020
PubMed

Keywords:
BET bromodomainsBRD4 D1 selectivityepigeneticsinhibitorsstructure-activity relationships

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