Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The long isoform of ZAP coordinates multiple enzymes to mediate complete decay of target transcripts.

Cell reports·2026

Same author

International Collaborative Study on Human Papillomavirus Analytical Thresholds for Sensitivity and Specificity in Cervical Screening.

Journal of medical virology·2026

Same author

Next generation sequencing approaches for the detection and characterization of enteroviruses in clinical, public health, and research settings: Expert view of the European non-polio enterovirus network (ENPEN).

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026

Same author

Impaired booster-induced SARS-CoV-2 antibody responses in rituximab-treated B-cell lymphoma patients despite peripheral B-Cell Recovery.

Radiology and oncology·2026

Same author

Bacterial microbiome analysis of vaginal, cervical, and endometrial samples in patients with adenomyosis during the window of implantation.

Microbiology spectrum·2026

Same author

Trends and determinants of hepatitis C virus infection among people living with HIV in Slovenia: a nationwide study, 1986-2024.

Acta dermatovenerologica Alpina, Pannonica, et Adriatica·2026

Search research articles

Related Experiment Video

Updated: Dec 7, 2025

A Protocol for Analyzing Hepatitis C Virus Replication

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Simplification of hepatitis C testing: a time to act.

¹Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica

|September 25, 2020

Summary

Hepatitis C virus (HCV) testing is simplifying with new rapid diagnostics and innovative tools. These advancements support global HCV elimination goals by improving accessibility and accuracy in diagnosis and treatment.

Area of Science:

Hepatology
Virology
Public Health

Background:

Hepatitis C virus (HCV) impacts 71 million globally, with potential for elimination by 2030.
Advances in diagnostics and antiviral therapies are crucial for HCV control.
Simplifying HCV testing is key to achieving public health goals.

Purpose of the Study:

To review current and emerging strategies for simplifying Hepatitis C virus (HCV) testing.
To discuss diagnostic solutions for diverse healthcare settings, including low- and middle-income countries.
To assess the feasibility of HCV elimination targets based on diagnostic advancements.

Main Methods:

Review of recent guidance documents from major professional societies.
Analysis of current anti-HCV antibody testing, including rapid diagnostic tests (RDTs).

More Related Videos

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

Related Experiment Videos

Last Updated: Dec 7, 2025

A Protocol for Analyzing Hepatitis C Virus Replication

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

Exploration of innovative diagnostic technologies for HCV RNA and core antigen detection.

Main Results:

Anti-HCV antibody testing is the recommended first-line approach.
Rapid diagnostic tests are approaching the performance of standard immunoassays.
Emerging technologies like loop-mediated isothermal amplification and CRISPR-Cas show promise for HCV detection.
Point-of-care diagnostics and mobile labs offer solutions for resource-limited settings.
Micro-elimination and macro-elimination strategies have demonstrated success in real-world settings.

Conclusions:

Simplified HCV testing is critical for achieving global elimination goals.
Innovative diagnostics and strategic approaches like micro- and macro-elimination are vital.
While elimination is plausible, timelines may vary by country due to resource and implementation challenges.