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The Buffalo study: Outcome and associated predictors in endodontic microsurgery- a cohort study.
A A Azim1, H Albanyan1,2, K A Azim3
1Division of Endodontics, University at Buffalo, Buffalo, NY, USA.
International Endodontic Journal
|September 25, 2020
Summary
Endodontic microsurgery (EMS) shows high success and survival rates. Major procedural errors negatively impact outcomes, while guided tissue regeneration (GTR) influences bone healing patterns but not overall success.
Area of Science:
- Endodontics
- Oral Surgery
- Radiology
Background:
- Endodontic microsurgery (EMS) is a specialized procedure for complex endodontic cases.
- Evaluating the outcomes and prognostic factors of EMS is crucial for optimizing treatment.
- Radiographic assessment methods, including periapical radiographs (PAs) and cone-beam computed tomography (CBCT), play a key role in outcome evaluation.
Purpose of the Study:
- To compare the outcomes of EMS assessed by PAs versus CBCT.
- To identify prognostic factors influencing the success of EMS.
- To determine the effect of guided tissue regeneration (GTR) on apical bone remodelling patterns.
Main Methods:
- Eighty-two patients (101 teeth) undergoing EMS were evaluated using clinical and radiographic (PA and CBCT) follow-ups.
- Two calibrated endodontists assessed radiographic healing, success, and survival rates.
- Statistical analyses, including regression, were used to identify prognostic factors and the impact of GTR.
Main Results:
- High survival (93%) and success rates (88% PA, 86% CBCT) were observed.
- CBCT demonstrated better inter-observer agreement than PAs for radiographic assessment.
- Major procedural errors were the sole negative predictor of EMS outcome; GTR affected bone remodelling patterns but not success rates.
Conclusions:
- EMS demonstrates high success and survival rates.
- Major procedural errors are critical factors affecting EMS outcomes.
- While GTR does not enhance success rates, it influences the quality of apical bone remodelling post-EMS.

