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Updated: Dec 7, 2025
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Increased Longevity and Pumping Performance of an Injection Molded Soft Total Artificial Heart
Leonard G Guex1, Lewis S Jones1, A Xavier Kohll1
1Department of Chemistry and Applied Biosciences, Institute for Chemical- and Bioengineering, ETH Zurich, Zurich, Switzerland.
Abstract:
In this work, we present an injection molded soft total artificial heart (sTAH) produced from high-temperature vulcanizing silicone using an industrial metal injection mold. At 60 beats per minute, the sTAH exhibited a total cardiac output of over 16 L/min against physiological pressures on a mock circulation and was pumped continuously for 110,000 actuation cycles. Finite element analysis was used to identify stress concentrations within the sTAH, allowing an optimized design to be proposed.
