Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

761
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
761
Modeling in Therapy01:26

Modeling in Therapy

279
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
279
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

599
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
599
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

410
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
410
Social Anxiety Disorder01:28

Social Anxiety Disorder

274
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
274
Antisocial Personality Disorder01:24

Antisocial Personality Disorder

416
Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
416

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autism-ness Does Not Exist, but Autism Does, Part 2: The Perception-Language Chimera Model Accounts for the Nature, Chronology, and Interrelation of Autistic Signs.

Autism & developmental language impairments·2026
Same author

Autistic Children With Speech Onset Delay Show Reversed Bias in Spectral Versus Temporal Auditory Processing.

Autism research : official journal of the International Society for Autism Research·2026
Same author

Autism-ness Does Not Exist, but Autism Does. Part 1: A Critic of the "Spectrum" Position Used to Describe, Diagnose, and Research Autism, and Its Alternative.

Autism & developmental language impairments·2025
Same author

Asymmetric developmental bifurcations in polarized environments: a new class of human variants, which may include autism.

Molecular psychiatry·2025
Same author

Calendar calculation: A systematic review of 100 years of research.

Neuroscience and biobehavioral reviews·2025
Same author

How is calendar calculation in autism possible? A language model.

Psychological review·2025
Same journal

Preface.

Handbook of clinical neurology·2026
Same journal

Foreword.

Handbook of clinical neurology·2026
Same journal

Fundus autofluorescence imaging.

Handbook of clinical neurology·2026
Same journal

The electroretinogram as a means to study the physiology of the retina.

Handbook of clinical neurology·2026
Same journal

Adaptive optics scanning light ophthalmoscopy.

Handbook of clinical neurology·2026
Same journal

Modeling the human retina in a dish: Advances and future directions.

Handbook of clinical neurology·2026
See all related articles

Related Experiment Video

Updated: Dec 7, 2025

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

16.9K

Autism spectrum disorder.

Laurent Mottron1

  • 1Department of Psychiatry and Addictology, University of Montreal, Montreal, QC, Canada.

Handbook of Clinical Neurology
|September 26, 2020
PubMed
Summary
This summary is machine-generated.

Autism Spectrum Disorder (ASD) presents with social and communication challenges, alongside repetitive behaviors. While its genetic origins are complex, ASD involves brain differences and unique information processing, with evolving symptoms throughout life.

Keywords:
Asperger syndromeAutismCNVDiagnosisIntelligencePrevalence

More Related Videos

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism
06:15

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

8.0K
Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.3K

Related Experiment Videos

Last Updated: Dec 7, 2025

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

16.9K
Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism
06:15

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

8.0K
Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.3K

Area of Science:

  • Neuroscience
  • Genetics
  • Developmental Psychology

Background:

  • Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social-communication atypicalities and restricted, repetitive behaviors.
  • The diagnostic criteria for ASD have broadened over 75 years, encompassing a wider spectrum of phenotypes with varying intellectual and speech abilities.
  • While often associated with other conditions, nonsyndromic autism is primarily genetic and transmissible, influenced by common polymorphisms and rare de novo mutations.

Purpose of the Study:

  • To provide a comprehensive overview of Autism Spectrum Disorder (ASD).
  • To discuss the genetic underpinnings and neurobiological correlates of ASD.
  • To describe the phenotypic evolution and lifelong support needs associated with ASD.

Main Methods:

  • Review of existing literature on autism.
  • Analysis of genetic factors, including polymorphisms and de novo mutations.
  • Examination of neurobiological changes and information processing variants in ASD.

Main Results:

  • ASD is linked to genetic factors, with both common small-effect polymorphisms and rare large-effect mutations contributing.
  • The condition involves significant brain reorganization and a distinct pattern of information processing.
  • The presentation of ASD evolves over an individual's lifespan, generally showing a reduction in autistic signs but often requiring ongoing support.

Conclusions:

  • Autism Spectrum Disorder is a complex neurodevelopmental condition with a significant genetic component.
  • Neurobiological differences, including brain reorganization and altered information processing, are central to ASD.
  • While there is no cure, individuals with ASD can achieve high levels of societal integration with appropriate support.