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Placenta-mediated complications: Nucleosomes and free DNA concentrations differ depending on subtypes

Sylvie Bouvier1,2,3, Eve Mousty4, Mathieu Fortier1

  • 1Department of Haematology, CHU Nimes, Univ Montpellier, Nîmes, France.

Journal of Thrombosis and Haemostasis : JTH
|September 26, 2020
PubMed
Summary

Nucleosomes and cell-free DNA (fDNA) levels rise in normal pregnancy. These biomarkers are elevated in placenta-mediated complications, with higher concentrations in preeclampsia than intrauterine growth restriction.

Keywords:
cell-free DNAhyper-coagulabilityintrauterine growth restrictionnucleosomespreeclampsiapregnancy

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