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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Pearls and Pitfalls in Pediatric Thyroid Imaging
Cicero T Silva1, Oscar M Navarro2
1Department of Radiology & Biomedical Imaging, Yale University School of Medicine, New Haven, CT.
Insights
Pediatric thyroid imaging is crucial for diagnosing congenital hypothyroidism and thyroid nodules. Special attention is needed as nodules in children are more often malignant, and risk assessment criteria may require adjustment.
Area of Science:
- Pediatric Radiology
- Endocrinology
- Thyroid Imaging
Background:
- Thyroid imaging in children is essential for evaluating congenital hypothyroidism, diffuse thyroid enlargement, and nodules.
- Congenital hypothyroidism is frequently due to thyroid dysgenesis.
- Diffuse thyroid enlargement in adolescents often results from Hashimoto disease, nodular hyperplasia, Graves disease, or papillary carcinoma.
Purpose of the Study:
- To highlight key aspects and potential challenges in pediatric thyroid imaging.
- To emphasize the importance of understanding unique pediatric imaging features for accurate diagnosis.
Main Methods:
- Review of current literature and clinical practices in pediatric thyroid imaging.
- Discussion of common indications and findings in the pediatric population.
Main Results:
- Thyroid nodules are less frequent but more likely malignant in children compared to adults.
- Current TI-RADS (Thyroid Imaging Reporting and Data System) criteria may underestimate malignancy risk in pediatric thyroid nodules, potentially leading to under-classification.
Conclusions:
- Accurate diagnosis and management of pediatric thyroid conditions rely on specialized knowledge of imaging characteristics.
- Awareness of the pitfalls in pediatric thyroid nodule risk stratification is critical for appropriate patient care.
Abstract:
This article discusses the role of imaging of the thyroid gland in children, highlighting pearls and pitfalls. In the pediatric age group, thyroid imaging is mainly performed for the evaluation of congenital hypothyroidism, diffuse thyroid enlargement, and thyroid nodules. Permanent congenital hypothyroidism is most often caused by thyroid dysgenesis. Diffuse thyroid enlargement is mainly seen in teenage girls, and most often caused by Hashimoto disease, nodular hyperplasia, Graves disease, or diffuse papillary carcinoma. Thyroid nodules are less common in children than they are in adults, but more likely to be malignant; TI-RADS criteria may underestimate the risk of malignancy in children, and lead to erroneous classification downgrading. Knowledge of unique features of thyroid imaging in the pediatric population is critical for accurate diagnosis and management recommendations.
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