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Neuropathy of the elderly.
1Laboratory of Clinical Neurophysiology (Professor Lionel-Naccache), Salpetriere Hospital, 47, boulevard de l'hôpital, 75013 Paris, France.
Revue Neurologique
|September 27, 2020
Summary
Peripheral nervous system aging is common in older adults, affecting nerve function but not quality of life. Diabetes is the leading cause of neuropathy in the elderly, increasing fall risks.
Area of Science:
- Neurology
- Geriatrics
- Nerve Disorders
Background:
- Peripheral nervous system aging is a common condition in individuals over 65.
- Age-related changes include decreased nerve conduction, altered reflex responses, and sensory deficits.
Purpose of the Study:
- To describe the characteristics and common causes of peripheral nervous system aging.
- To highlight the clinical implications of peripheral neuropathy in the elderly population.
Main Methods:
- Review of existing literature on peripheral nervous system aging and neuropathy in the elderly.
- Analysis of etiological factors, clinical manifestations, and functional impact.
Main Results:
- Two-thirds of individuals over 65 exhibit signs of peripheral nervous system aging, with increased prevalence beyond 80 years.
- Diabetes is the most frequent cause of neuropathy in this age group, followed by idiopathic cases.
- Despite neurological changes, quality of life is generally unaffected, but neuropathy increases fall frequency and risk of bone damage.
Conclusions:
- Peripheral nervous system aging is a prevalent phenomenon with distinct characteristics in the elderly.
- While generally mild, neuropathy in older adults necessitates attention due to potential risks like falls.
- Early detection of causes like late-onset hereditary neuropathies and diabetes management are crucial.
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