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Related Concept Videos

Pulse01:16

Pulse

1.7K
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
1.7K
Pulse01:05

Pulse

3.3K
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
3.3K
Pulse amplitude and quality01:17

Pulse amplitude and quality

2.8K
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
2.8K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.7K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.7K
Regulation of Pulse01:20

Regulation of Pulse

1.9K
Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.
1.9K
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

701
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
701

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Related Experiment Video

Updated: Dec 7, 2025

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
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Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

Published on: December 10, 2014

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Brain Tissue Pulsation in Healthy Volunteers.

Poppy Turner1, Caroline Banahan2, Meshal Alharbi3

  • 1Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; Department of Engineering, University of Leicester, Leicester, UK.

Ultrasound in Medicine & Biology
|September 27, 2020
PubMed
Summary
This summary is machine-generated.

Brain tissue pulsations (BTPs) vary widely in healthy adults, influenced by pulse pressure. This study provides reference data for BTPs measured via transcranial Doppler, aiding future clinical applications and modeling.

Keywords:
Brain magnetic resonance imagingBrain tissue displacementBrain tissue pulsationsHealthy volunteersTranscranial Tissue DopplerUltrasound

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Cardiovascular Physiology

Background:

  • The brain exhibits pulsations synchronized with the cardiac cycle.
  • Measuring cardiac-induced brain tissue pulsations (BTPs) is an emerging area of research.
  • Establishing reference data for BTPs in healthy individuals is crucial for clinical applications.

Purpose of the Study:

  • To generate reference data for brain tissue pulsations (BTPs) in healthy adults.
  • To investigate the influence of age, sex, heart rate, mean arterial pressure, and pulse pressure on BTPs.
  • To correlate transcranial Doppler BTP measurements with anatomical data.

Main Methods:

  • Utilized transcranial tissue Doppler to measure BTPs at forehead and temporal positions in 107 healthy adults (aged 20-81 years).
  • Developed a multivariate regression model to analyze BTP variations.
  • Conducted brain MRI on a subset of participants to validate probe positions and anatomical correlations.

Main Results:

  • BTP amplitudes showed significant inter-individual variability (approximately 4 to 150 µm).
  • Pulse pressure was identified as a strong determinant of BTP amplitude.
  • MRI confirmed regional BTP variations related to measurement depth and probe location.

Conclusions:

  • Reference data for BTPs in healthy adults have been established.
  • Pulse pressure is a key factor influencing BTPs.
  • Understanding regional BTP variations is important for accurate measurement and interpretation.