Is the P388 murine tumor no longer adequate as a drug discovery model?

Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.

Oncogene·2016

Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola.

Phytochemistry letters·2012

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

Leukemia·2010

Methylene-gem-difluorocyclopropane analogues of nucleosides: synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity.

Journal of medicinal chemistry·2001

High-performance liquid chromatographic method for the estimation of the novel investigational anti-cancer agent SR271425 and its metabolites in mouse plasma.

Journal of chromatography. B, Biomedical sciences and applications·2001

Isolation of dolastatin 10 from the marine cyanobacterium Symploca species VP642 and total stereochemistry and biological evaluation of its analogue symplostatin 1.

Journal of natural products·2001

Parthenolide enhances imatinib activity in gastrointestinal stromal tumor models through stress-associated apoptosis.

Investigational new drugs·2026

First-in-human phase I study of DT-9081, a selective EP4 receptor antagonist, in advanced solid tumors.

Investigational new drugs·2026

Qishen Yiqi Dripping Pills ameliorate doxorubicin-induced cardiotoxicity: a study based on bioinformatics and experimental verification.

Investigational new drugs·2026

Influence of LGALS3 polymorphisms on chemotherapy-induced peripheral neuropathy in patients with metastatic pancreatic cancer treated with gemcitabine and nab-paclitaxel: an exploratory biomarker analysis of the GENESECT study.

Investigational new drugs·2026

Inhibition of SHP2 enhances the effects of selective receptor tyrosine kinase inhibitors in untreated preclinical models of RET-mutated thyroid cancer.

Investigational new drugs·2026

Novel EGFR tyrosine kinase inhibitors exhibiting intrinsic fluorescence.

Investigational new drugs·2026

Dual molecular and clinical machine-learning prognostic modeling in pancreatic ductal adenocarcinoma: a chaperone-mediated autophagy-based framework integrating multi-cohort molecular signatures and a single-center clinical nomogram.

Frontiers in cell and developmental biology·2026

Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering.

Research square·2026

Postoperative pain trajectories and associated factors in patients undergoing lung cancer surgery: a scoping review.

Frontiers in psychology·2026

An endocannabinoid-nitric oxide signaling switch triggers reciprocal inhibitory-excitatory plasticity at dopamine neuron inputs following prenatal cannabinoid exposure.

bioRxiv : the preprint server for biology·2026

Allostatic load in female cancer patients: a systematic review.

Frontiers in endocrinology·2026

Combined C-reactive protein, procalcitonin, and microalbuminuria panel for contrast-induced nephropathy risk stratification after percutaneous coronary intervention.

Frontiers in cardiovascular medicine·2026

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Is the P388 murine tumor no longer adequate as a drug discovery model?

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Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.

Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola.

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

Methylene-gem-difluorocyclopropane analogues of nucleosides: synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity.

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Is the P388 murine tumor no longer adequate as a drug discovery model?

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