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Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

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Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
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Centrally acting muscle relaxants reduce muscle tone and tension by interfering with the postsynaptic reflexes in the central nervous system.
Centrally acting drugs are classified into spasmolytic and antispasmodic drugs. Spasmolytic drugs such as baclofen, diazepam, and tizanidine inhibit spinal motor neurons and decrease muscle tone. Spasmolytic drugs are administered for severe and chronic spasms due to multiple sclerosis, cerebral palsy, stroke, and spinal cord and muscle injuries. However,...
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Spasmolytic agents are drugs used to alleviate muscle spasms and spasticity. They can be categorized into different chemical groups based on their mechanisms of action. Centrally acting spasmolytics primarily affect the spinal cord, while others directly target skeletal muscle cells.
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Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
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Related Experiment Video

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Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model
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Spinal Manipulation and Select Manual Therapies: Current Perspectives.

Nathan Hinkeldey1, Casey Okamoto2, Jamal Khan2

  • 1VA Central Iowa Health Care System, 3600 30th Street, Des Moines, IA 50310, USA; Palmer College of Chiropractic, 1000 Brady Street, Davenport, IA 52803, USA.

Physical Medicine and Rehabilitation Clinics of North America
|September 28, 2020
PubMed
Summary

Human touch in healthcare offers significant benefits, including pain mitigation and patient comfort. This review explores manual therapy

Keywords:
Chiropractic manipulationHuman touchManual therapyMassageOsteopathic manipulationSpinal manipulation

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Area of Science:

  • Medicine
  • Neuroscience
  • Physical Therapy

Background:

  • Touch is integral to the doctor-patient relationship, influencing patient comfort and trust.
  • Neuromodulatory effects of touch can alleviate pain and promote relaxation.
  • The physical examination and treatment often involve therapeutic touch.

Purpose of the Study:

  • To review current evidence on the role and impact of human touch in healthcare.
  • To explore the mechanisms of action for manual therapy.
  • To assess the effectiveness of manual therapy in pain management and various health conditions.

Main Methods:

  • Literature review of studies on human touch and manual therapy.
  • Analysis of evidence for manual therapy's impact on pain and specific conditions.
  • Examination of dose-response relationships in manual therapy treatment plans.

Main Results:

  • Manual therapy demonstrates efficacy in pain management across various conditions.
  • Evidence supports specific treatment plans with dose-response data for manual therapy.
  • Human touch has measurable neuromodulatory effects that benefit patients.

Conclusions:

  • Manual therapy, a form of therapeutic touch, is a valuable intervention for pain management.
  • Further research should explore the full impact of manual therapy on patient outcomes and the healthcare system.
  • Integrating evidence-based manual therapy can enhance patient care and potentially reduce healthcare costs.