Related Experiment Video
Updated: Dec 7, 2025

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
Triage Standing Orders Decrease Time to Antibiotics in Neonates in Pediatric Emergency Department
Insights
Implementing nurse-driven triage standing orders significantly reduced antibiotic administration time for infants with serious bacterial infections. This quality improvement initiative improved timely care for high-risk newborns in the emergency department.
Area of Science:
- Pediatrics
- Infectious Diseases
- Healthcare Quality Improvement
Background:
- Neonates (0-28 days) face high risks of serious bacterial infections, necessitating prompt evaluation and antibiotic treatment.
- Current practices often result in delayed antibiotic administration, with baseline rates at 19% within 120 minutes.
- A quality improvement initiative aimed to enhance the timeliness of antibiotic delivery for these vulnerable infants.
Purpose of the Study:
- To decrease the time to antibiotic administration for infants (0-28 days) evaluated for serious bacterial infections in the emergency department.
- To increase the percentage of infants receiving antibiotics within 120 minutes of arrival.
Main Methods:
- A quality improvement team utilized nurse-driven triage standing orders and multiple Plan-Do-Study-Act cycles.
- The study focused on infants aged 0-28 days undergoing evaluation for serious bacterial infections.
- Statistical process control charts were used for data analysis.
Main Results:
- The implementation of triage standing orders and educational interventions led to 84% of infants receiving antibiotics within 120 minutes.
- The average time to antibiotic administration was reduced from 192 minutes to 74 minutes.
- Initial goals for timely antibiotic delivery were surpassed.
Conclusions:
- Nurse-driven triage standing orders are effective in improving timely antibiotic administration for infants with serious bacterial infections.
- Empowering nurses to initiate work-ups fosters a joint-responsibility model, leading to sustained improvements.
- A cultural shift towards nurse-initiated protocols enhances efficiency and patient care in the emergency department.
Introduction:
Infants aged 0 days to 28 days are at high risk for serious bacterial infection and require an extensive evaluation, including blood, urine, and cerebrospinal fluid cultures, and admission for empiric antibiotics. Although there are no guidelines that recommend a specific time to antibiotics for these infants, quicker administration is presumed to improve care and outcomes. At baseline, 19% of these infants in our emergency department received antibiotics within 120 minutes of arrival, with an average time to antibiotics of 192 minutes. A quality improvement team convened to increase our percentage of infants who receive antibiotics within 120 minutes of arrival.
Methods:
The team evaluated all infants aged 0 days to 28 days who received a diagnostic evaluation for a serious bacterial infection and empiric antibiotics in our emergency department. A nurse-driven team implemented multiple Plan-Do-Study-Act cycles to improve use of triage standing orders and improve time to antibiotics. Data were analyzed using statistical process control charts.
Results:
Through use of triage standing orders and multiple educational interventions, the team surpassed initial goals, and 84% of the infants undergoing a serious bacterial infection evaluation received antibiotics within 120 minutes of ED arrival. The average time to antibiotics improved to 74 minutes.
Discussion:
The use of triage standing orders improves time to antibiotics for infants undergoing a serious bacterial infection evaluation. Increased use, associated with nurse empowerment to drive the flow of these patients, leads to a joint-responsibility model within the emergency department. The cultural shift to allow nurse-initiated work-ups leads to sustained improvement in time to antibiotics.
More Related Videos
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Factors Affecting Drug Response: Overview
Pharmacokinetics in Pediatric Patients: Drug Metabolism

