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Transjugular intrahepatic portosystemic shunt for Budd-Chiari syndrome: A comprehensive review

Riccardo Inchingolo1, Alessandro Posa2, Martin Mariappan3

  • 1Interventional Radiology Unit, "F. Miulli" Regional Hospital, Acquaviva delle Fonti 70021, Italy.

World Journal of Gastroenterology
|September 28, 2020
PubMed

Insights

Budd-Chiari syndrome (BCS), a rare condition of blocked hepatic veins, has high mortality if untreated. Transjugular intrahepatic portosystemic shunt (TIPS) offers a safe and effective treatment option for BCS patients.

Area of Science:

  • Hepatology
  • Interventional Radiology
  • Vascular Medicine

Background:

  • Budd-Chiari syndrome (BCS) is a rare condition characterized by hepatic venous outflow obstruction.
  • Untreated BCS carries a high mortality rate, necessitating effective management strategies.

Purpose of the Study:

  • To review the pathophysiology, diagnosis, and treatment of BCS.
  • To focus on the techniques and outcomes of transjugular intrahepatic portosystemic shunt (TIPS) for BCS management.

Main Methods:

  • Literature review focusing on BCS pathophysiology, diagnosis, and treatment options.
  • Special emphasis on published data concerning TIPS techniques and outcomes in BCS patients.

Main Results:

  • BCS management involves a step-wise approach, including anticoagulation and interventional radiology.
  • Transjugular intrahepatic portosystemic shunt (TIPS) is a safe and highly effective treatment for BCS.

Conclusions:

  • TIPS should be recommended for BCS patients, including those awaiting liver transplantation.
  • Further research is needed to address unresolved issues in BCS management and TIPS application.

Keywords:
Budd-Chiari syndromeInterventional radiologyLiverOrthotopic liver transplantationPortal hypertensionTransjugular intrahepatic portosystemic shunt

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