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Related Experiment Video

Updated: Dec 7, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

Long Non-Coding RNAs in Brown Adipose Tissue.

Songjia Lai¹, Kun Du¹, Yu Shi¹

¹Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, People's Republic of China.

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy

|September 28, 2020

Summary

Long non-coding RNAs (lncRNAs) regulate fat homeostasis and energy expenditure. This review explores lncRNAs

Keywords:

BAT lncRNAs obesity thermogenesis

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Last Updated: Dec 7, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

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Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Published on: October 7, 2014

Area of Science:

Molecular Biology
Genetics
Endocrinology

Background:

Obesity is a global health concern linked to disrupted fat homeostasis.
Brown adipose tissue (BAT) plays a crucial role in energy expenditure and combating obesity.
Long non-coding RNAs (lncRNAs) are emerging as key regulators in various biological processes.

Purpose of the Study:

To review the properties and functions of lncRNAs in brown adipose tissue.
To highlight the role of lncRNAs in adipogenesis, adipose tissue browning, and thermogenesis.
To explore the potential of lncRNAs as therapeutic targets for obesity.

Main Methods:

Literature review of studies on lncRNAs and brown adipose tissue.
Analysis of lncRNA functions in brown adipogenesis, white adipose browning, and thermogenesis.
Discussion of lncRNA-based therapeutic strategies for obesity.

Main Results:

Specific lncRNAs are involved in regulating brown adipose tissue function.
lncRNAs influence key processes such as brown adipogenesis, beige adipogenesis, and thermogenesis.
lncRNAs offer promising avenues for novel obesity drug development.

Conclusions:

lncRNAs are critical regulators of fat homeostasis and energy expenditure.
Targeting lncRNAs in BAT presents a novel strategy for obesity treatment.
Further research into BAT lncRNAs could lead to effective anti-obesity therapies.