Acute Deterioration of Kidney Function after Total Hip Arthroplasty
S Takeshita1, M Sonohata1, M Kitajima1
1Department of Orthopaedic Surgery, Saga University, Saga, Japan.
Malaysian Orthopaedic Journal
|September 28, 2020
Summary
Diabetes and NSAID use before hip surgery increase kidney function decline risk. Managing these controllable factors can help prevent post-operative kidney injury.
Area of Science:
- Nephrology
- Orthopedic Surgery
- Anesthesiology
Background:
- Post-operative acute kidney injury (AKI) is a significant complication following total hip arthroplasty (THA).
- Identifying modifiable risk factors is crucial for improving peri-operative management and patient outcomes.
Purpose of the Study:
- To identify pre-operative and intra-operative factors associated with AKI after THA.
- To determine factors linked to acute kidney function deterioration post-THA.
Main Methods:
- Retrospective observational study of 203 patients undergoing unilateral primary THA.
- AKI assessed using Risk, Injury, Failure, Loss of kidney function, End-stage kidney disease (RIFLE) criteria.
- Acute kidney function deterioration defined as ≥10ml/min/1.73m² reduction in estimated glomerular filtration rate (eGFR).
Main Results:
- Prevalence of chronic renal dysfunction (eGFR <60ml/min/1.73m²) was 20%.
- Incidence of AKI was 0.49% and acute kidney function deterioration was 6.9%.
- Diabetes mellitus and pre-operative nonsteroidal anti-inflammatory drug (NSAID) use were significant risk factors for kidney function deterioration.
Conclusions:
- Diabetes mellitus and NSAID use are controllable risk factors for post-THA kidney injury.
- Multidisciplinary approaches can effectively minimize peri-operative AKI and kidney function decline.
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