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Inhibitor bias in luciferase-based luminescence assays

Dimitar Yonchev1, Jürgen Bajorath1

  • 1Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology & Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Endenicher Allee 19c, D-53115 Bonn, Germany.

Future Science OA
|September 28, 2020
PubMed
Summary

No abstract available in PubMed .

Keywords:
bioluminescence assayscomputational analysisfalse positivesfirefly luciferasehit ratesluciferase inhibitorsmechanisms of actionpublic assay data

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