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Ofloxacin-ornidazole fixed-dose combination medication-induced pancreatitis with positive rechallenge

Nikhil Bush1, Vishal Sharma1, K Chandrahasan2

  • 1Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Family Medicine and Primary Care
|September 28, 2020
PubMed

Insights

This case report details a patient who developed acute pancreatitis after taking ofloxacin-ornidazole fixed-dose combination (FDC) antibiotics. This adverse drug reaction highlights the underreporting of pancreatitis linked to this common diarrhea medication.

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Internal Medicine

Background:

  • Ofloxacin-ornidazole fixed-dose combination (FDC) is widely prescribed in India for mixed-infection diarrhea.
  • Adverse drug reactions (ADRs) associated with these FDCs are frequently underreported.
Keywords:
Adverse eventofloxacinornidazolepancreatitispositive rechallenge

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