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Updated: Dec 7, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
Published on: September 8, 2021
Experimental data on demographic, functional and structures of patients with schizophrenia and schizophrenia-dementia
Juan Rivas1,2,3, Jose Libreros4, Maria Trujillo4
1Psychiatry Unit, Fundación Valle del Lili-Universidad ICESI, Kra. 98 No 18-49, Cali, Colombia.
Abstract:
Schizophrenia is a severe mental disorder that includes behavioural and cognitive manifestations generated by genetic or environmental factors, caused by a dysfunction of the dopaminergic system which contributes to the genesis of psychosis, producing a profound effect on affected individuals and society [6]. In this work, demographic data, neuropsychological profiles and measurements of brain morphometry, using Magnetic Resonance Image (MRI), of three groups of patients are presented. A control group with 15 patients, a schizophrenic without dementia group with 10 patients, and a schizophrenic with dementia group with 10 patients constituted the observed sample. Results of 21 neuropsychological tests and 11 brain structure measurements are included. The data set is a comprehensive source for advancing in a further understanding of schizophrenia and schizophrenia-dementia neuro-pathologies.
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