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Updated: Dec 7, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
Noise-Induced Hearing Loss and its Prevention: Current Issues in Mammalian Hearing
Colleen G Le Prell1, Troy A Hackett2, Ramnarayan Ramachandran2
1School of Behavioral and Brain Sciences, University of Texas at Dallas, Dallas, TX, USA.
Abstract:
Noise-induced hearing loss (NIHL) has been well investigated across diverse mammalian species and the potential for prevention of NIHL is of broad interest. To most efficiently develop novel therapeutic interventions, a good understanding of the current state of knowledge regarding mechanisms of injury is essential. The overarching goals of this review are to 1) concisely summarize the current state of knowledge, and 2) provide opinions on the most significant future trends and developments.

